By Irem OnurA nonhormonal treatment of endometriosis: Dichloroacetate
By Irem Onur
In women with endometriosis, peritoneal mesothelial cells show higher glycolysis, lower mitochondrial respiration, decreased enzymatic activity of pyruvate dehydrogenase and increased production of lactate compared to women without the disease. Transforming growth factorβ1 and lactate are elevated in the peritoneal…
Key Points Lay Summary